作者:2025-12-03浏览次数:780

胡凯

*为通讯作者

1.       Zeying Chen, Yun Tang, Jiaxuan Jiang, Di Zhang, Yiran Chu, Boda Li, Qi Zhang, Huayong Zhang, Kai Hu*(胡凯). Inhibition of Histone Methyltransferase G9a Activates Autophagy and Provides Protection in Dry Eye Disease. Investigative Ophthalmology & Visual Science. 2025 Nov 3;66(14):52. 2区,影响因子4.700

2.       Jiao Liu, Rongjie Guo, Wenhao Shen, Jiaxuan Jiang, Yiran Chu, Changyu Wu, Kai Hu*(胡凯). A Modified Swan Incision Combined with Lateral Rectus Suspension for Exotropia: A Retrospective Cohort Study Demonstrating Shorter Operative Time and Faster Recovery. Frontiers in Medicine. 2025 Sep 19;12:1571642.3区,影响因子3.900

3.       Junpeng Liu, Wei Liu, Yefan Zhang, Junwen Ouyang, Boxiao Zhao, Changyu Wu, Boda Li, Jiaxuan Jiang*, Kai Hu*(胡凯). Injectable High-Adhesion Fibrinogen-Silk Fibroin Hydrogel Loaded with Curcumin Accelerates Pterygium Repair via Dual Anti-Inflammatory/Antiproliferative Mechanisms. ACS Applied Materials & Interfaces. 2025 Sep 17;17(37):51805-51819.2区,影响因子8.200

4.       Junwen Ouyang, Changyu Wu, Jingya Yang, Yun He, Junpeng Liu, Boxiao Zhao, Youmei Zheng, Boda Li, Jiaxuan Jiang*, Kai Hu*(胡凯). Suppression of MERTK Inhibits Proliferation and Migration of Pterygium Fibroblasts. Experimental Eye Research. 2025 Nov;260:110595.2 区,影响因子 2.700

5.       Yun He, Di Zhang, Jiao Liu, Junwen Ouyang, Chengxiao Zhang, Qian Tan*, Jiaxuan Jiang*, Kai Hu*(胡凯). Ocular Soluble Microneedle Patch Loaded with Immunogenic Cell Death Inducer PKHB1 Peptide for Alleviating Herpes Simplex Keratitis.ACS Applied Materials & Interfaces.2025;17(30):42824-42837.2区,影响因子8.200

6.       Junpeng Liu, Boda Li, Boxiao Zhao, Wei Liu, Fan Yang, Jingya Yang, Jiaxuan Jiang*, Kai Hu*(胡凯). IL-33 alleviates corneal nerve damage in herpes simplex keratitis. International Immunopharmacology. 2025 Jun 26:159:114833.2区,影响因子4.700

7.       Ruibo Chen, Tao Xu, Chunyan Xi, Kejun Liu, Kai Hu*(胡凯), Bing Chen*. An applied study of phacoemulsification cataract surgery with the mortise and tenon limbal incision.Scientific reports. 2025 Jun 3;15(1):19464. 3区,影响因子3.900

8.       Di Zhang, Taige Chen, Qi Liang, Xuebing Feng, Jiaxuan Jiang, Zeying Chen, Yun Tang, Yiran Chu, Bin Wang*, Kai Hu*(胡凯). A first-in-human, prospective pilot trial of umbilical cord-derived mesenchymal stem cell eye drops therapy for patients with refractory non-Sjögren's and Sjögren's syndrome dry eye disease. Stem cell research & therapy. 2025 Apr 23;16(1):202.2区,影响因子7.300

9.       Di Zhang, Qi Liang, Jiaxuan Jiang, Wei Liu, Yiran Chu, Zeying Chen, Boda Li, Taige Chen, Jia-Ruei Tsao, Kai Hu*(胡凯). SIRT3 mitigates dry eye disease through the activation of autophagy by deacetylation of FOXO1. Experimental Eye Research. 2025 Mar 8;254:110328.2区,影响因子2.700

10.    Boda Li, Junpeng Liu, Di Zhang, Yiran Chu, Zeying Chen, Jiaruei Tsao, Taige Chen, Jiaxuan Jiang*, Kai Hu*(胡凯). Evodiamine promotes autophagy and alleviates oxidative stress in dry eye disease through the p53-mTOR pathway. Investigative Ophthalmology & Visual Science. 2025 Mar 3;66(3):44.2区,影响因子4.700

11.    Boda Li, Jiaxuan Jiang, Qi Zhang, Yiran Chu, Zeying Chen, Kai Hu*(胡凯).Therapeutic effects of umbilical cord serum for dry eye disease: a systemic review and meta-analysis. Ophthalmic Research. 2024 Dec 2;68(1):7183.3区,影响因子1.900

12.    Jiaxuan Jiang, Di Zhang, Wei Liu, Jingya Yang, Fan Yang, Junpeng Liu, Kai Hu*(胡凯).Overexpression of NLRP12 enhances macrophage immune response and alleviates herpes simplex keratitis. Frontiers in Cellular and Infection Microbiology. 2024 Jul 25;14:1416105.2区,影响因子4.800

13.    Jiaxuan Jiang, Wenhao Shen, Yun He, Junpeng Liu, Junwen Ouyang, Chengxiao Zhang, Kai Hu*(胡凯). Overexpression of NLRP12 enhances antiviral immunity and alleviates herpes simplex keratitis via pyroptosis/IL-18/IFN-γ signaling. International immunopharmacology. 2024 Aug 20;137:112428.2区,影响因子4.700

14.    Taige Chen, Nan Zhou, Qi Liang, Qi Li, Boda Li, Yiran Chu, Di Zhang, Zeying Chen, Jia-Ruei Tsao, Xuebing Feng*, Kai Hu*(胡凯).Biochanin A: Disrupting the Inflammatory Vicious Cycle for Dry Eye Disease. European Journal of Pharmacology. 2024 Aug 15;977:176583.2区,影响因子4.700

15.    Zeying Chen, Chengxiao Zhang, Jiaxuan Jiang, Junwen Ouyang, Di Zhang, Taige Chen, Yiran Chu, Kai Hu*(胡凯). The Efficacy of Vitamin D Supplementation in Dry Eye Disease: A Systematic Review and Meta-Analysis. Contact Lens and Anterior Eye. 2024 Oct;47(5):102169.3区,影响因子3.700

16.    Nan Zhou, Taige Chen, Qiao You, Deyan Chen, Lifei Liu*, Kai Hu*(胡凯). Enterovirus A71 infection-induced dry eye-like symptoms by damaging the lacrimal glands. Frontiers in Cellular and Infection Microbiology.2024 Apr 2;14:1340075.2区,影响因子4.800

17.    Wenhao Shen, Chenchen Wang, Jiaxuan Jiang, Yun He, Qi Liang, Kai Hu*(胡凯). Targeted delivery of herpes simplex virus glycoprotein D to CD169+ macrophages using ganglioside liposomes alleviates herpes simplex keratitis in mice. Journal of Controlled Release. 2024 Jan;365:208-218.1区,影响因子11.500

18.    Rongjie Guo, Jiaxuan Jiang, Yanan Zhang, Qi Liang, Jiao Liu, Kai Hu*(胡凯). The effects of chalazion and the excision surgery on the ocular surface. Heliyon. 2023 Sep 9;9(9):e19971.3区,影响因子4.000

19.    Nan Zhou, Deyuan Zheng, Qiao You, Taige Chen, Jiaxuan Jiang, Wenhao Shen, Di Zhang, Junpeng Liu, Deyan Chen*, Kai Hu*(胡凯). Therapeutic Potential of Biochanin A in Herpes Simplex Keratitis. Pharmaceuticals Basel. 2023 Sep 1;16(9):1240.3区,影响因子4.600

20.    Qi Liang, Rongjie Guo, Jia-Ruei Tsao, Yun He, Chenchen Wang, Jiaxuan Jiang, Di Zhang, Taige Chen, Tingting Yue*, Kai Hu*(胡凯). Salidroside alleviates oxidative stress in dry eye disease by activating autophagy through AMPK-Sirt1 pathway. International Immunopharmacology. 2023 Aug;121:110397.2区,影响因子5.600

21.    Rongjie Guo, Jiaxuan Jiang, Yanan Zhang, Qi Liang, Taige Chen, Kai Hu*(胡凯). Evaluation of corneal dendritic cell density and subbasal nerve density in contact lens wearers using IVCM: A systematic review and meta-analysis. Frontiers in Medicine. 2023 Mar 13;10:1149803.3区,影响因子3.900

22.    Rongjie Guo, Qi Liang, Yun He, Chenchen Wang, Jiaxuan Jiang, Taige Chen, Di Zhang, Kai Hu*(胡凯). Mesenchymal stromal cells-derived extracellular vesicles regulate dendritic cell functions in dry eye disease. Cells.2022 Dec 22;12(1):33.2区,影响因子6.000

23.    Yun He, Chenchen Wang, Qi Liang, Rongjie Guo, Jiaxuan Jiang, Wenhao Shen, Kai Hu*(胡凯). PKHB1 Peptide Induces Antiviral Effects Through Induction of Immunogenic Cell Death in Herpes Simplex Keratitis. Frontiers in Pharmacology.2022 Dec 1;13:1048978.2区,影响因子5.600

24.    Qin Qin*, Kai Hu(胡凯), Zifang He, Feifei Chen, Wenwen Zhang, Yajun Liu, Zhenggao Xie*. Resolvin D1 protects against Aspergillus fumigatus keratitis in diabetes by blocking the MAPK-NF-κB pathway. Experimental Eye Research. 2022 Mar;216:108941.2区,影响因子3.400,共同第一)

25.    Chenchen Wang, Qi Liang, Dong Sun, Yun He, Jiaxuan Jiang, Rongjie Guo, Tejsu Malla, Pedram Hamrah, Xun Liu, Zhenping Huang*, Kai Hu*(胡凯). Nectin-1 and Non-muscle Myosin Heavy Chain-B: Major Mediators of Herpes Simplex Virus-1 Entry Into Corneal Nerves. Frontiers in Microbiology. 2022 Feb 28;13:830699.2区,影响因子5.200

26.    Wenting Cheng, Lei Zhou, Kai Hu(胡凯), Dehua Kong, Wei Huang, Chuanjun Xu, Hao Li*, Jinlong Li*. Enzyme-Initiated Assembly of an Extracellular-Like Two-Dimensional Nanonetwork as a Method to Detect Procancerous Activity. ACS Sensors. 2021 May 28;6(5):1815-1822.1区,影响因子8.900,共同第一)

27.    Wenting Cheng, Jiehua Ma, Dehua Kong, Zhaoli Zhang, Adeel Khan, Changhua Yi, Kai Hu*(胡凯), Yongxiang Yi*, Jinlong Li*. One step electrochemical detection for matrix metalloproteinase 2 based on anodic stripping of silver nanoparticles mediated by host-guest interactions. Sensors and Actuators B:Chemical. 2021 Mar 1;330:129379.1区,影响因子8.400,共同通讯)

28.    Arsia Jamali, Kai Hu(胡凯) Victor G Sendra, Tomas Blanco, Maria J Lopez, Gustavo Ortiz, Yureeda Qazi, Lixin Zheng, Aslihan Turhan, Deshea L Harris, Pedram Hamrah*. Characterization of Resident Corneal Plasmacytoid Dendritic Cells and Their Pivotal Role in Herpes Simplex Keratitis. Cell Reports. 2020 Sep 1;32(9):108099.1区,影响因子8.800,共同第一,Cell子刊)

29.    Jinlong Li*, Jiehua Ma, Yongchen Zhang, Zhaoli Zhang, Kai Hu*(胡凯). Highly sensitive electrochemical analysis of telomerase activity based on magnetic bead separation and exonuclease III-aided target recycling amplification. Bioelectrochemistry. 2019 Dec;130:107341.2区,影响因子5.000

30.    Jinlong li*, Kai Hu(胡凯), Yongchen Zhang, Zhaoli Zhang, Yongfeng Yang*. A Highly Sensitive Electrochemical Sensor Based on DNA Y-Junction for Detection of Estrogen Receptor Using Target Protein Protection Strategy. Analytica Chimica Acta.2019 Dec 4;1086:110-115.2区,影响因子6.200,共同第一)

31.    Kai Hu*(胡凯), Jinlong Li, Xianwen Yuan. MicroRNA-411 plays a protective role in Diabetic Retinopathy through Targeted Regulating Robo4. European Review for Medical and Pharmacological Sciences. 2019 Nov;23(21):9171-9179.4区,影响因子3.300

32.    Jinlong Li*, Kai Hu(胡凯), Yongchen Zhang, Zhaoli Zhang, Hao Li*. Highly sensitive detection of Smoothened based on the drug binding and rolling cycle amplification. Analytical and Bioanalytical Chemistry. 2019 Sep;411(22):5721-5727.2区,影响因子4.300,共同第一)

33.    Jinlong Li*, Kai Hu(胡凯), Zhaoli Zhang, Xiaoyan Teng, Xia Zhang*. Click DNA cycling in combination with gold nanoparticles loaded with quadruplex DNA motifs enable sensitive electrochemical quantitation of the tuberculosis-associated biomarker CFP-10 in sputum. Microchimica Acta. 2019 Aug 31;186(9):662.2区,影响因子5.700,共同第一)

34.    Tejsu Malla, Jing Jiang, Kai Hu*(胡凯). Clinical outcome of combined conjunctival autograft transplantation and amniotic membrane transplantation in pterygium surgery. International Journal of Ophthalmology. 2018 Mar 18;11(3):395-400.3区,影响因子1.400

35.    Ru Tang, Yujia Zhai, Lili Dong, Tejsu Malla, Kai Hu*(胡凯). Immunization with dendritic cell-based DNA vaccine pRSC-NLDC145.gD-IL21 protects mice against herpes simplex virus keratitis. Immunotherapy. 2018 Mar;10(3):189-200.4区,影响因子2.800

36.    Lili Dong, Ru Tang,Yujia Zhai, Tejsu Malla, Kai Hu*(胡凯). DNA vaccine expressing herpes simplex virus 1 glycoprotein C and D protects mice against herpes simplex keratitis. International Journal of Ophthalmology. 2017 Nov 18;10(11):1633-1639.3区,影响因子1.330

37.    Kai Hu*(胡凯), Tejsu Malla, Yujia Zhai, Lili Dong, Ru Tang. Topical Administration Is A Promising Inoculating Route versus Intramuscular Inoculation for The Nanoparticle-Carried DNA Vaccine to Prevent Corneal Infections. Ophthalmic Research. 2015 Dec 10;55(2):99-110.4区,影响因子1.961

38.    Kai Hu(胡凯), Deshea L. Harris, Takefumi Yamaguchi, Ulrich von Andrian, Pedram Hamrah*. A Dual Role for Corneal Dendritic Cells in Herpes Simplex Keratitis: Local Suppression of Corneal Damage and Promotion of Systemic Viral Dissemination. Plos one.2015 Sep 2;10(9):e0137123.3区,影响因子2.740

39.    Kai Hu(胡凯), Jun Dou*, Fangliu Yu, Xiangfeng He, Xianwen Yuan, Yaqing Wang, Chunsheng Liu, Ning Gu*.An ocular mucosal administration of nanoparticles containing DNA vaccine pRSC-gD-IL-21 confers protection against mucosal challenge with herpes simplex virus type 1 in mice. Vaccine. 2011 Feb 4;29(7):1455-62.2区,影响因子3.413

40.    Kai Hu(胡凯), Xiangfeng He, Fangliu Yu,Xianwen Yuan, Weihua Hu, Chunsheng Liu, Fengshu Zhao, Jun Dou*. Immunization with DNA Vaccine Expressing Herpes Simplex Virus Type 1 gD and IL-21 Protects against Mouse Herpes Keratitis. Immunological Investigations. 2011;40(3):265-78.3区,影响因子1.780