南京大学医学院附属鼓楼医院眼科行政主任、省级临床重点专科学科带头人；医学博士、主任医师、博士生导师；亚太地区眼外伤协会会员，中华医学会眼科分会眼外伤学组委员，中国医师协会眼外伤专业委员会委员，江苏省医学会眼科分会副主任委员兼白内障学组副组长，江苏省医师协会眼科分会副主任委员兼眼底病学组副组长，江苏省研究型医院学会玻璃体视网膜疾病专业委员会主任委员，南京医学会眼科分会候任主委；《中华眼外伤职业眼病杂志》编委、《中华实验眼科杂志》通讯编委；2022 年获“中国优秀眼科医师”称号，先后入选江苏省“科教兴卫工程”医学重点人才、“333 工程”高层次人才、“六大人才高峰”人才、“卫生拔尖”人才、“六个一工程”人才。

长期致力于玻璃体视网膜疾病及眼外伤的临床与基础研究，发表学术论文 160 余篇，其中SCI论文60余篇。主持国家自然科学基金/省自然科学基金各1项。主译出版专著 10部，获授权发明/实用新型专利 29件；创新及改进眼科手术技术 20 余项，部分临床研究成果发表于 JAMA Ophthalmology、Retina、J Cataract Refract Surg 等国际期刊。基础研究部分成果发表于Free Radical Bio Med、 J Transl Med、Mol Pharm、Cell Death Discov、Stem Cells等期刊。

亚太地区眼外伤协会会员

中华医学会眼科分会眼外伤学组委员

中国医师协会眼外伤专业委员会委员

江苏省医学会眼科分会副主任委员兼白内障学组副组长

江苏省医师协会眼科分会副主任委员兼眼底病学组副组长

江苏省研究型医院学会玻璃体视网膜疾病专业委员会主任委员

南京医学会眼科分会候任主委

《中华眼外伤职业眼病杂志》编委

《中华实验眼科杂志》通讯编委。

1. Liao YL, Xiang JJ, Xia Y, Liu C, He C, Tong J, Chen YQ, Yao GH*, Xie ZG*. Mitochondrial-derived peptide MOTS-c rescues vascular endothelial damage via PLA2G6 in diabetic retinopathy. Cell Death Discov, 2026，epub

2. Liu C, Xiang JJ, Liu SY, He C, Liao YL, Zhang RP, Xia Y, Chen YQ, Yao GH*, Xie ZG*. ITPR2 regulates microglial pyroptosis by Ca2+ transfer through mitochondria-ER contacts in diabetic retinopathy. J Transl Med, 2026, epub

3. Liu SY, Bao YB, Yilihaer Y, Guo WH, Ma CC, Xue CY*, Yang ZH*, Chen YQ*, Xie ZG*. VEGFA-targeted M3-F4 ionizable lipid nanoparticles improve diabetic retinopathy. Mol Pharm, 2026, 23(6):3367-3382.

4. Qin Q, Wang Y, Liu Y, An W, He Z, Chen F, Cheng X, Chen D*, Xie Z*. Resolvin D1 alleviates lipopolysaccharide-induced in vitro corneal inflammation by modulating macrophage polarization through upregulation of c-Fos expression. Bioimpacts, 2025, 15(0):32639.

5. Tong J, Chen Y, Zhang Y, Liu C, He C, Liu Y, Liao Y, Chen F*, Yao G*, Xie Z*. MSC-derived small extracellular vesicles attenuate diabetic retinopathy through miR-29a-3p regulated microglia M1-like polarization. Exp Eye Res, 2025, 260(0):110586

6. Bao Y, Lei H, Guo Y, Liu Y, Chen H, Xie Z*. DisCoVisc substituted for perfluorocarbon liquid stabilizing the detached retina during vitrectomy for rhegmatogenous retinal detachment. Retina, 2025, 45(12):2429-2434.

7. Liu C, Xiang J, Chen Y, He C, Tong J, Liao Y, Lei H, Sun L*, Yao G*, Xie Z*. MiR-125a-5p in MSC-derived small extracellular vesicles alleviates Müller cells injury in diabetic retinopathy by modulating mitophagy via PTP1B pathway. Cell Death Discov, 2025, 11:226.

8. Tong J, Chen Y, Ling X, Huang Z, Yao G*, Xie Z*. Mesenchymal stem cell-derived exosomal miR-125b-5p suppressed retinal microvascular endothelial cell ferroptosis in diabetic retinopathy. Stem Cells, 2025，43（6）：1-15.

9. Chen Y, Liu C, Tong J, He C, Ling X, Xiang J, Xue C, Yao G*, Sun L*, Xie Z*. Inhibition of Cullin3 neddylation alleviates diabetic retinopathy by activating Nrf2 signaling to combat ROS-induced oxidative stress and inflammation. Inflammation, 2025, 48(5):3194-3205.

10. Chen YQ, Tong J, Liu C, He C, Xiang JJ, Yao GH*, Zhang HY*, Xie ZG*. MSC-derived small extracellular vesicles mitigate diabetic retinopathy by stabilizing Nrf2 through miR-143-3p-mediated inhibition of neddylation. Free Rad Bio Med, 2024, 219:76-87.

11. Tong J, Yao GH, Chen YQ, Xie HR, Zheng XY, Sun LY*, Huang ZP*, Xie ZG*. Mesenchymal stem cells regulate microglial polarization via inhibition of the HMGB1/TLR4 signaling pathway in diabetic retinopathy. Inflammation, 2024, 47(5):1728-1743.

12. Chen YQ, Yao GH, Tong J, Zhang HY*, Xie ZG*. MSC-derived small extracellular vesicles alleviate diabetic retinopathy by delivering miR-22-3p to inhibit NLRP3 inflammasome activation. Stem Cells, 2024,42(1):64-75.

13. Liu Y, Lei H, Guo Y, Bao Y, Xie Z*. A novel embedded-style corneal contact lens: For emergency vitreoretinal surgery in patients with severe corneal opacities. Retina, 2024, 44(4):744-746.

14. Liu Y, Jiang F, Chen F, Liu Y, Zhang W, Zhang S, He Z, Cheng X, Xie Z*. Minimal posterior pole vitrectomy and fixing the inverted ILM flap with DisCoVisc for macular hole: no gas or air tamponade. Retina, 2023,43(12):2208-2214.

15. Du W, Chen F, Zhu J, Xie Z*. Application of modified silicone oil retention sutures in traumatic aphakic eyes with iris loss. Retina, 2022, 42(11):2218-2220.

16. Zhang W, Jiang F, Xie Z*. A modified trocar and cannula system with lateral micropores for 1-step drainage of suprachoroidal fluid during primary vitrectomy. JAMA Ophthalmol, 2022, 140(9):900-901.

17. Chen F, Hu HH, Zhu J, Du W, Xie ZG*. Removing the retained subfoveal perfluorocarbon liquid with peeled internal limiting membrane reposition and flute aspiration. Retina, 2022, 42(8):1612-1215.

18. Chen F, Zhang Y, Du W, Zhu J, Gan CL, Xie ZG*. Indocyanine green-assisted internal limiting membrane peeling to induce posterior vitreous detachment in the cases with strong vitreoretinal adhesion. Retina, 2022, 42(8):1616-1618.

1. 2026年国家自然科学基金项目：面上项目，H4K16乳酰化介导SLC39A14增强子活化驱动糖尿病视网膜病变微血管损伤的机制研究. 2027-2030，49万，编号：82671392，主持

2. 2025年江苏省自然科学基金项目：面上项目，色氨酸/TrpRS/SGK1色氨酰化轴驱动糖尿病视网膜病变的机制研究. 2025-2028，15万，编号：BK20251719，主持

3. 2022年江苏省卫生健康委医学科研项目：重点项目，基于新型囊袋内灌注ICG-DW溶液技术精准清除晶状体上皮细胞预防白内障术后晶状体囊膜混浊的基础与临床研究，江苏省卫生健康委，2023-2025年，20万，编号：ZD2022-22，主持

4. 2021年南京市卫生科技发展专项资金项目：重点项目，基于新型囊袋注射蒸馏水精准清除晶状体上皮细胞技术预防晶状体囊膜混浊的临床研究，南京市卫生健康委，2022-2024年，10万，编号：ZKX21018，主持

1.后极部玻璃体切除联合黏弹剂固定内界膜瓣无气体填充治疗黄斑裂孔。南京市卫健委，2024年度新技术奖，一等奖，第一

2.最小量玻璃体切除术在治疗黄斑疾病中的应用. 江苏省卫健委，2025年度医学引进新技术奖，二等奖，第一