吴俊华

文章来源:南京大学医学院发布时间:2019-06-24浏览次数:10

博(硕)士研究生导师简介

姓名

Name

吴俊华

Junhua WU

研究方向:

Research Direction

1. 药理学(Pharmacology)

2. 肿瘤治疗学

(Tumor Therapy)

联系方式

Email: wujunhua(at)nju.edu.cn

学术兼职:中国药理学会会员   中国细胞生物学会会员

《世界华人消化杂志》编委

个人简介

  1. 工作简历

1998-2007  南京大学生科院  本科、博士

2007-      南京大学医学院  讲师、副教授



  1. 科研情况简介

  • 主持国家自然科学基金、江苏省重点研发计划江苏省自然科学基金和教育部博士点基金以及其他各类课题数十项

  • 以第一作者或者通讯作者在Nature Communications等刊物发表SCI论文30余篇

  • 2015年发表的一篇关于肿瘤治疗新方法的文章在2016年被列为ESI高引用文章(学科前1%

  • SCI文章共计被SCI引用1000余次,篇均SCI引用次数近30余次

  • 参编专著1王军,吴俊华  先导化合物的优化 功能海洋生物分子发现与应用(著作),科学出版社

  • 主译10万字的专注1 吴俊华、李方、裘吉人.《医学伦理》(译林出版社出版,原著为牛津大学出版社出版的Medical ethics



  1. 研究兴趣

1.化合物或者天然产物活性与功能的发现、评价与作用机制研究

2.肿瘤发生、发展机制与治疗方法的研究



代表性论文(Publictions)

  1. Wu JH#, Li PF#, Dong CL#, Jiang HT, Bin Xue, Gao X, Qin M, Wang W*, Bin Chen*, CaoY*.Rationallydesigned synthetic protein hydrogelswithpredictablemechanicalproperties. NatureCommunications.2018, 9(1):620. Doi:10.1038/s41467-018-02917-6.IF2017: 12.124.



  1.  Guang Zhang, Zhongxia Wang, Weibo Chen, Yin Cao, Junyi Wu, Guanghui Qiang, Anlai Ji, Junhua Wu*, Chunping Jiang*. Dual Effects of Gossypol on Human Hepatocellular Carcinoma via Endoplasmic Reticulum Stress and Autophagy. International Journal of Biochemistry & Cell Biology, 113 (2019) 4857. IF2018: 3.144二区


  1. Wei Hu, Zhongxia Wang, Shan Zhang, Xian Lu, Junyi Wu, Kuanyong Yu, Anlai Ji, Wei Lu, Zhong Wang, Junhua Wu* & Chunping Jiang*.IQGAP1 promotes pancreatic cancer progression and epithelial-mesenchymal transition (EMT) through Wntβ-catenin signaling. Scientific Reports, (2019) 9:7539. IF2017: 4.011.


  1. Wu JY#, Wang ZX#, Ma D, Qu Z, Wu JH*, Jiang CP*. Targeted co-delivery of Beclin 1 siRNA and FTY720 to hepatocellular carcinoma by calcium phosphate nanoparticles for enhanced anticancer efficacy. International Journal of Nanomedicine, 2018:13 1265–1280. IF2017: 4.300.


  1. Wu JY#, Ji AL#, Wang ZX#, Qiang GH, Qu Z, Wu JH*, Jiang CP*. Exosome-Mimetic Nanovesicles from Hepatocytes promote hepatocyte proliferation in vitro and liver regeneration in vivo. Scientific Reports, 2018, 6;8(1):2471. Doi: 10.1038/s41598-018-20505-y.   IF2017: 4.259



  1. Chun Xu#, Xian Lu#, Wei Liu, Anxian Chen, Gang Meng, Hailin Zhang, Binghua Li, Yonghui Zhang, Junhua Wu*, Jiwu Wei*.CD8+ T cells mediate the antitumor activity of frankincense and myrrh in hepatocellular carcinoma.Journal of Translational Medicine,2018, 16: 132.IF2017: 3.786. 肝癌治疗新方法


  1. Lu X#, Wo G#, Li B, Xu C, Wu J*, Jiang C*, Wei J*.The anti-inflammatory NHE-06 restores antitumor immunity by targeting NF-κB/IL-6/STAT3 signaling in hepatocellular carcinoma. Biomedicine & Pharmacotherapy, 2018, 102: 420-427. IF2017: 2.759. 肝癌治疗新方法


  1. Zhen Qu#, Junhua Wu#, Junyi Wu, Anlai Ji, Guanghui Qiang, Yong Jiang*, Chunping Jiang* and Yitao Ding*. Exosomal miR-665 as a novel minimally invasive biomarker for hepatocellular carcinoma diagnosis and prognosis. Oncotarget, 2017, Vol. 8, (No. 46), pp: 80666-80678. #Co-first author  IF2017: 5. 168  二区


  1. Aiping Chen#, Yonghui Zhang#, Gang Meng, Dengxu Jiang, Hailin Zhang, MeihongZheng, Mao Xia1, Aiqin Jiang, Junhua Wu*, Christian Beltinger, Jiwu Wei*. Oncolytic measles virus enhancesantitumour responses ofadoptive CD8+NKG2D+ cellsin hepatocellular carcinomatreatment. Scientific Reports, 2017, 7: 5170. DOI:10.1038/s41598-017-05500-z.IF2017: 4.259


  1. JUNYI WU#, ZHEN QU#, ZI WEI FEI#, JUN HUA WU* and CHUN PING JIANG*. Role of stem cell-derived exosomes in cancer. ONCOLOGY LETTERS. 2017, 13: 2855-2866.IF2017: 1.390


  1. Diancheng Wang#, Gang Meng#, Meihong Zheng, Yonghui Zhang, Aiping Chen,Junhua Wu*, Jiwu Wei*.The Glutaminase-1 Inhibitor 968 Enhances Dihydroartemisinin-Mediated Antitumor Efficacy in Hepatocellular Carcinoma Cells. PLoS ONE(2016) 11(11): e0166423.doi:10.1371/journal.pone.0166423.  IF2017: 2.806  三区


  1. Zhen Qu#, Junhua Wu#, Junyi Wu, Dongjun Luo, Chunping Jiang* and Yitao Ding*. Exosomes derived from HCC cells inducesorafenib resistance in hepatocellularcarcinoma both in vivo and in vitro. Journal of Experimental & Clinical Cancer Research(2016) 35:159. #Co-first author  IF2017: 5.189  二区


  1. Dongjun Luo,Qing Ni,Anlai Ji,Wen Gu,Junhua Wu*,Chunping Jiang*. Dehydroabietic Acid Derivative QC4 Induces Gastric Cancer Cell Death via Oncosis and Apoptosis. BioMed Research International, Volume 2016, Article ID 2581061, 10 pages, http://dx.doi.org/10.1155/2016/2581061.*Corresponding Author  IF2017: 2.476  三区


  1. Junhua Wu, Aiping Chen, Meng Qin, Rong Huang, Guang Zhang, Bin Xue, Xiang Gao, Ying Li, Yi Cao and Wei Wang. Hierarchical construction of a mechanically stable peptide-graphene oxide hybrid hydrogel for drug delivery and pulsatile triggered release in vivo. Nanoscale2015 (7), DOI: 10.1039/C4NR05798H.   IF2017: 7. 367  一区


  1. Junhua Wu, Liwen Li, Chunping Jiang*. Identification and Evaluation of Serum MicroRNA-29 Family for Glioma Screening, 2015(52), Molecular Neurobiology, DOI 10.1007/s12035-014-8937-9.  IF2017: 6.190  二区