徐格林

文章来源:南京大学医学院发布时间:2017-07-03浏览次数:2

 

博士研究生导师简介

姓名

徐格林

研究方向

1.脑血管病

2.血管内介入技术

 

   专业:

神经病学

联系方式

电话:025-80863531

Email: gelinxu@nju.edu.cn

学 术 兼 职 :

2012年11月-现在  江苏省神经病学分会,委员

2012年6月-现在   全军神经病学分会脑血管病学组, 委员

2010年10月-现在   全军精神医学分会,委员

2007年9月-现在    中国老年学会心脑血管病分会,委员

 

个人简介

1. 工作简历

1987.09   第四军医大学学员

1993.07   第四军医大学心理学教研室见习助教

1996.09   第四军医大学研究生队学员

1999.08   第四军医大学心理学教研室助教

2000.08   第四军医大学博士队学员

2003.06   南京军区南京总医院神经内科主治医师

2005.12   南京军区南京总医院神经内科副主任医师

2013.10   南京军区南京总医院神经内科主任医师

2. 科研情况简介

针对脑血管病、神经损伤修复、动脉粥样硬化等临床常见问题展开研究。任现职以来,获得国家自然科学基金2项,江苏省自然科学基金3项,南京军区重点科研基金1项。作为子课题负责人,参与一项国家科技支撑计划,作为子课题负责人,参加江苏省临床中心建设。2011年以来,以第一作者或通讯作者身份发表SCI论文24篇。

 

3. 研究兴趣

    主要从事脑血管病和神经血管介入方面的临床和研究工作。2013年,在国际上提出中国卒中带(China Stroke Belt)的理论,认为在我国东北、华北、西北和西藏地区存在一个连续的卒中带,其卒中发病风险明显高于其他地区,相应论文发表于Stroke杂志。2003年入选Global Burden of DiseasesGBD)专家。担任GBD专家以来,在Lancet杂志上以共同作者发表论文3篇。

代表性论文

[1]. Cao L, Zhang Z, Cai B, Bai W, Zhang Y, Sun W, Xie X, Sun W, Cai Q, Li Z, Liu D, Xiong Y, Ma M, Liu X, Xu G通讯作者. Association of heme oxygenase-1 gene rs2071746 polymorphism with vascular outcomes in patients with atherosclerotic stroke. J Neurol Sci. 2014 Jun 29. pii: S0022-510X(14)00416-X. doi:10.1016/j.jns.2014.06.046. [Epub ahead of print] PubMed PMID: 25016572.

[2]. Cao L, Zhang Z, Sun W, Bai W, Sun W, Zhang Y, Wang X, Cai B, Xie X, Duan Z, Cai Q, Liu D, Xiong Y, Ma M, Liu X, Xu G通讯作者. Impacts of COX-1 gene polymorphisms on vascular outcomes in patients with ischemic stroke and treated with aspirin. Gene. 2014 Jun 12. pii: S0378-1119(14)00687-8. doi: 10.1016/j.gene.2014.06.023.

[3]. Zhang Z, Xu G等同第一作者, Yang F, Zhu W, Liu X. Quantitative analysis of dietary protein intake and stroke risk. Neurology. 2014 Jun 11. pii:10.1212/WNL.0000000000000551.SCI IF=8.5

[4]. Xu G, Ma M, Liu X, Hankey GJ. Is there a stroke belt in china and why? Stroke. 2013 Jul;44(7):1775-83.  (SCI IF=6.158)

[5]. Li Y, Sun W, Yin Q, Wang Y, Cai Q, Sun W, Huang Z, Liu W, Xiong Y, Xu G通讯作者, Liu X. Safety and efficacy of simultaneous bilateral carotid angioplasty and stenting. J Thromb Thrombolysis. 2013 Apr 4. [Epub ahead of print] PubMed PMID: 23553247. (SCI IF=1.985)

[6]. Jiang Y, Zhu W, Zhu J, Wu L, Xu G通讯作者, Liu X. Feasibility of delivering mesenchymal stem cells via catheter to the proximal end of lesion artery in patients with stroke in the territory of middle cerebral artery. Cell Transplant. 2013;22(12):2291-8. (SCI IF=4.422)

[7]. Zhang Z, Xu G 等同第一作者, Liu X. Chocolate intake reduces risk of cardiovascular disease: Evidence from 10 observational studies. Int J Cardiol. 2013 Oct 15;168(6):5448-50. (SCI IF=5.509)

[8]. Wang X, Zhang Z, Liu W, Xiong Y, Sun W, Huang X, Jiang Y, Ni G, Sun W, Zhou L, Wu L, Zhu W, Li H, Liu X, Xu G通讯作者. Impacts and interactions of PDGFRB, MMP-3, TIMP-2, and RNF213 polymorphisms on the risk of Moyamoya disease in Han Chinese human subjects. Gene. 2013 Sep 10;526(2):437-42. (SCI IF=2.196)

[9]. Zhang Z, Xu G等同第一作者, Ma M, Yang J, Liu X. Dietary Fiber Intake Reduces Risk for Gastric Cancer: A Meta-analysis. Gastroenterology. 2013 Jul;145(1):113-120.e3. (SCI IF=12.821)

[10]. Zhang Z, Xu G等同第一作者, Liu D, Fan X, Zhu W, Liu X. Angiotensin-converting enzyme insertion/deletion polymorphism contributes to ischemic stroke risk: a meta-analysis of 50 case-control studies. PLoS One. 2012;7(10):e46495. (SCI IF=3.73)

[11]. Gong X, Ma M, Fan X, Li M, Liu Q, Liu X, Xu G通讯作者. Down-regulation of IGF-1/IGF-1R in hippocampus of rats with vascular dementia. Neurosci Lett. 2012;513(1):20-4. (SCI IF=2.026)

[12]. Tian L, Guo R, Yue X, Lv Q, Ye X, Wang Z, Chen Z, Wu B, Xu G通讯作者, Liu X. Intranasal administration of nerve growth factor ameliorate β-amyloid deposition after traumatic brain injury in rats. Brain Res. Brain Res. 2012;1440:47-55. (SCI IF=2.935)

[13]. Liu W, Xu G, Yue X, Wang X, Ma M, Zhang R, Wang H, Zhou C, Liu X. Hyperintense vessels on FLAIR: A useful non-invasive method for assessing intracerebral collaterals. Eur J Radiol. 2011;80(3):786-791. (SCI IF=2.512)

[14]. Xu G, Zhao W, Zheng L, Fan X, Yin Q, Liu X. Decreasing radiation doses in digital subtraction angiographies consecutively performed by trainees. Radiation Protection Dosimetry 2012,148(2)181-184. (SCI IF=0.909)

[15]. Zhu J, Jiang Y, Wu L, Lu T, Xu G通讯作者, Liu X. Suppression of local inflammation contributes to the neuroprotective effect of ginsenoside Rb1 in rats with cerebral ischemia. Neuroscience. 2012;202:342-351. (SCI IF=3.122)

[16]. Ni G, Liu W, Huang X, Zhu S, Yue X, Chen Z, Chen M, Liu X, Xu G通讯作者. Increased levels of circulating SDF-1α and CD34+ CXCR4+ cells in patients with moyamoya disease. Eur J Neurol. 2011;18(11):1304-1309. (SCI IF=4.162)

[17]. Jiang Y, Wei N, Zhu J, Lu T, Chen Z, Xu G通讯作者, Liu X. Effects of Brain-derived Neurotrophic Factor on Local Inflammation in Experimental Stroke of Rat. Mediators Inflamm. 2010; 2010:372423. (SCI IF=3.882)

[18]. Xu G, Yin Q, Liu X. Narrowing the gap of stroke management between developed and developing countries. Cerebrovasc Dis. 2010;29(1):101-102. (SCI IF=2.814)

[19]. Chen Z, Lu T, Yue X, Wei N, Jiang Y, Chen M, Ni G, Liu X, Xu G通讯作者. Neuroprotective effect of ginsenoside Rb1 on glutamate-induced neurotoxicity: with emphasis on autophagy. Neurosci Lett. 2010 4;482(3):264-268. (SCI IF=2.026)

[20]. Xu G, Zhao W, Zhou Z, Zhang R, Zhu W, Liu X. Danshen extracts decrease blood C reactive protein and prevent ischemic stroke recurrence: a controlled pilot study. Phytother Res. 2009;23(12):1721-1725. (SCI IF=2.068)

[21]. Xu G, Zhou Z, Zhu W, Fan X, Liu X. Plasma C-reactive protein is related to cognitive deterioration and dementia in patients with mild cognitive impairment. J Neurol Sci. 2009;284(1-2):77-80.  (SCI IF=2.243)

[22]. Xu G, Liu X, Yin Q, Zhu W, Zhang R, Fan X. Alcohol consumption and transition of mild cognitive impairment to dementia. Psychiatry Clin Neurosci. 2009;63(1):43-49. (SCI IF=2.04)

[23]. Xu G, Zheng L, Zhou Z, Liu X. Stenting for a symptomatic posterior cerebral artery stenosis. Catheter Cardiovasc Interv. 2009;73(6):745-748. (SCI IF=2.514)

[24]. Xu G, Liu X, Zheng L, Fan X, Yin Q. Successful recanalization of a chronic in-stent occlusion at the vertebral artery ostium. Interventional Neuroradiology. 2009;15: 462-465. (SCI IF=0.773)

[25]. Xu G, Cheng S, Liu X. Focus on endovascular solutions for cerebrovascular diseases. Cerebrovasc Dis. 2008;26(6):667-668. (SCI IF=2.814)

[26]. Xu G, Zhang H, Zhang S, Fan X, Liu X. Plasma fibrinogen is associated with cognitive decline and risk for dementia in patients with mild cognitive impairment. Int J Clin Pract. 2008;62(7):1070-1075.  (SCI IF=2.427)

[27]. Xu G. Building a Platform for East-West Communication in Stroke Research. Cerebrovasc Dis, 2008;25(3):279-280. (SCI IF=2.814)

[28]. Xu G, Liu X. Impacts of population aging on the subtypes of stroke. Stroke. 2008 Jul;39(7):e102-105. (SCI IF=6.158)

[29]. Xu G, Liu X, Zhu W, Yin Q, Zhang R, Fan X. Feasibility of treating hyperfibrinogenemia with intermittently administered batroxobin in patients with ischemic stroke/transient ischemic attack for secondary prevention. Blood Coagul Fibrinolysis. 2007;18(2):193-197. (SCI IF=1.248)

[30]. Xu G, Liu X, Meyer JS, Yin Q, Zhang R. Cognitive performance after carotid angioplasty and stenting with brain protection devices. Neurol Res. 2007;29(3):251-255.        (SCI IF=1.182)

[31]. Xu G, Liu X, Wu W, Zhang R, Yin Q. Recurrence after ischemic stroke in chinese patients: impact of uncontrolled modifiable risk factors. Cerebrovasc Dis.

承担科研项目

 

1.江苏省科技发展计划-BE2013713-经颅磁刺激在脑卒中后语言和运动功能康复中的应用研究100万

2.江苏省重点临床临床中心-神经内科中心 430万

3.国家自然科学基金-(30870848)-经鼻给予病毒载体介导的BDNF基因在脑缺血大鼠中枢神经系统的表达 35万

4.国家自然科学基金(81070922)缺血性脑血管病患者使用阿司匹林后发生颅内出血的遗传机制 31万

 

获奖情况

[1].刘新峰,刘国庆,梁慧康,徐格林,史兆荣,樊新颖,朱武生,马敏敏,殷  勤,张仁良。脑梗死血管学特征谱的新发现与血运重建治疗的新策略。国家科学技术进步奖二等奖,2014年。

[2].刘新峰,刘国庆,梁慧康,马敏敏,朱武生,徐格林,张仁良,刘文华,孙芳,李芸,殷勤。脑梗死血运重建的新策略及其机理研究。江苏省科学技术奖一等奖,2013年。

[3].刘新峰,徐格林,殷勤,樊新颖,杨昉,刘玲,郭芮兵,李敏,刘德志,许剑,葛颂,周广怡,周志明,朱双根,张仁良,樊小兵,马敏敏,朱武生。脑卒中血管学病因及干预研究。高等学校科学研究优秀成果科技进步一等奖,2011年。

[4].徐格林,殷勤,张仁良。颅内Willis环以外动脉狭窄的支架治疗。江苏省卫生厅医学新技术引进奖一等奖,2009年。

[5].刘新峰,徐格林,易学明,张仁良,樊新颖,樊小兵,殷勤,朱武生,郭芮兵。经鼻给予多肽生长因子救治神经毒剂和脑缺血所致的脑损伤。军队科技进步一等奖,2009年。

[6].刘新峰,张仁良,徐格林,樊小兵,殷勤,朱武生,樊新颖,刘亚红,陈光辉。基于卒中登记的脑血管病系列研究。军队医疗成果二等奖,2008年。

[7].刘新峰,徐格林,朱武生,殷勤,张仁良,樊小兵,杨昉,刘亚红,陈光辉。缺血性脑血管病颅内、外动脉狭窄的诊断和介入治疗。军队医疗成果二等奖,2006年。